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98% up Alogliptin Benzoate 850649-62-6 CAS NO.850649-62-6
- FOB Price: USD: 825.00-1,100.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,
- Available Specifications:
99% up(1-5)Kilogram99% up(5-20)Kilogram99% up(20-100)Kilogram
- Product Details
Keywords
- Alogliptin Benzoate
- Alogliptin
- 850649-62-6
Quick Details
- ProName: 98% up Alogliptin Benzoate 850649-62-6
- CasNo: 850649-62-6
- Molecular Formula: C18H21N5O2.C7H6O2
- Appearance: Yellow powder
- Application: API
- DeliveryTime: in 7 days after your payment
- PackAge: 1kg/bag ;5kg/drum
- Port: Shanghai/Beijing/Hangzhou
- ProductionCapacity: 10 Metric Ton/Month
- Purity: 99% up
- Storage: low temperature storage
- Transportation: in low tempreture
- LimitNum: 1 Kilogram
Superiority
Why is SINOWAY:
1) Specialized in pharmaceutical and healthcare industrial for 34 years.
2) ISO 9001:2015 & SGS audited supplier .
3) Accept various payment terms : T.T 30-60 days.
4) We have warehouse in USA with quickly shipment .
5) We can do different terms of FOB ,CIF/CIP ,DDP ...
Details
|
Product name |
Alogliptin benzoate |
|
CAS No. |
850649-62-6 |
|
Molecular Formula |
C18H21N5O2.C7H6O2 |
|
Molecular Weight |
461.52 |
|
Quality Standard |
98% up by HPLC |
|
Appearance |
White powder |
|
|
|
ITEMS |
SPECIFICATION |
RESULT |
|
Appearance |
White or off-white crystalline powder |
Complies |
|
Melting point |
181.0°C ~185.0°C |
182-184°C, melting and decomposition |
|
Specific rotation |
+13° ~ +18° |
+14.6° |
|
Identification |
1. UV: maximum absorption at the wavelength of 278+2nm |
Complies |
|
2. IR: be consistent with standard |
Complies |
|
|
3. HPLC： the retention time of the main peak of the solution should be consistent with the retention time of the main peak of the reference solution. |
Complies |
|
|
Water |
≤ 0.5% |
0.15% |
|
Residue on ignition |
≤ 0.2% |
0.09% |
|
Heavy metals |
≤ 20 ppm |
Complies |
|
Enantiomer |
≤ 0.5% |
ND |
|
Residual solvents |
Ethanol ≤ 5000ppm |
985 ppm |
|
DMF ≤ 880 ppm |
ND |
|
|
DCM ≤ 600 ppm |
ND |
|
|
TOL ≤ 890 ppm |
ND |
|
|
IPA ≤ 5000 ppm |
ND |
|
|
Related substances |
Single impurity ≤ 0.1% |
0.01% |
|
Total impurities≤ 2.0% |
0.05% |
|
|
Assay |
98.0% - 102.0% |
100.01% |
|
Conclusion |
The sample complies with the above specification |
|
|
|
Alogliptin benzoate is a selective inhibitor of dipeptidyl peptidase-4 (DPP-4). Eating stimulates the small intestine to secrete elevated concentrations of incretins, such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), into the bloodstream. These hormones cause islet beta cells to release insulin in a glucose-dependent manner, but these hormones are inactivated by the DPP-4 enzyme within minutes. Inhibition of DPP-4 activity by alogliptin slows the inactivation of these incretins, thereby increasing blood concentrations of these hormones and reducing fasting and postprandial blood glucose in a glucose-dependent manner in patients with type II diabetes.
