China (Mainland)
Diamondsupplier 
Antineoplastic API Oxaliplatin CAS:61825-94-3 CAS NO.61825-94-3
- Min.Order: 1 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,Other
- Available Specifications:
- Product Details
Keywords
- Oxaliplatin CAS:61825-94-3
- EP standard with 99.5% up Oxaliplatin
- Antineoplastic API Oxaliplatin
Quick Details
- ProName: Antineoplastic API Oxaliplatin CAS:618...
- CasNo: 61825-94-3
- Molecular Formula: C8H12N2O4Pt
- Appearance: White or almost white crystalline powd...
- Application: Third generation platinum complex. An ...
- DeliveryTime: within 7-10 days after order
- PackAge: 1kg/tin or per customer's requirement
- Port: Beijing/Shanghai/Hangzhou/Shenzhen
- ProductionCapacity: 1000 Kilogram/Month
- Purity: 99.5% up
- Transportation: room temperature
- LimitNum: 1 Kilogram
- Related Substances: Total of impurities: NMT0.30%
- Valid Period: 2 years
Superiority
1) Specialized in pharmaceutical industry since from 1987
2) ISO 9001:2015 & SGS audited supplier
3) Accept better payment terms : T.T 30-60 days.on the basic of pass SINOSURE credit investigation.
5) We have warehouse in USA with quickly shipment .
6) We can do different terms of FOB ,CIF/CIP ,DDP ...
Details
- Product Details
|
COA of Oxaliplatin |
|
TEST ITEM |
SPECIFICATION |
RESULTS |
|
Description |
White or almost white crystalline powder |
White crystalline powder |
|
Solubility |
Slightly soluble in water ,very slightly soluble in methanol, practically insoluble in ethanol |
Complies |
|
Identification |
A.The infrared absorption spectrum as the same as Oxaliplatin CRS B.Test for specific optical rotation |
A.Complies
B.Complies |
|
Apearance of solution |
The solution is clear and colourless |
Complies |
|
Acidity |
Not more than 0.6ml of 0.01M NaOH is required to change the colour of the indicator to pink |
Complies |
|
Specific optical rotation |
+74.5°~+78.0° |
+75.4° |
|
Related substances |
ImpurityA:NMT0.10% ImpurityB: NMT0.10% ImpurityC: NMT0.10% Any other impurity:NMT0.10% Total of other impurities: NMT0.10% (include impurity C) Total of impurities: NMT0.30% |
ImpurityA 0.01% ImpurityB:0.01% ImpurityC: 0.001% Any other impurities: 0.003% Total of other impurities: 0.01% Total of impurities: 0.03% |
|
Impurity D |
NMT0.10% |
N.D |
|
Silver |
NMT5.0ppm |
0.08ppm |
|
Loss on drying |
NMT0.5% |
0.09% |
|
Assay |
98.0~102.0% (dried substance) |
99.7% |
|
Bacterial endotoxins |
<1.0IU/mg |
Complies |
|
Total aerobic microbial count |
≤50cfu/g |
Complies |
|
Total combined yeasts and moulds count |
≤10cfu/g |
Complies |
|
Conclusion |
Complies with EP7.2. |
|
|
Usage |
Function of Oxaliplatin
Oxaliplatin is the third-generation platinum-based anticancer drug, a platinum compound of diaminocyclohexane, that is, a 1,2-diaminocyclohexane group is substituted for the amino group of cisplatin. It has the same effect as other platinum drugs, that is, it takes DNA as the target site of action, and platinum atoms form a cross-link with DNA to antagonize its replication and transcription. Combined application with fluorouracil (5-FU) has a synergistic effect; in vitro and in vivo studies have shown no cross-resistance with cisplatin. Oxaliplatin has a good effect on colorectal cancer and ovarian cancer, and has a certain effect on gastric cancer, non-Hodgkin's lymphoma, non-small cell lung cancer, and head and neck tumors. Colorectal cancer patients who are not effective for 5-FU treatment are still effective for other platinum-resistant patients.
