China (Mainland)
Diamondsupplier 
GMP ,DMF Rapamycin Sirolimus with very competitive price CAS NO.53123-88-9
- Min.Order: 10 Gram
- Payment Terms: L/C,T/T
- Available Specifications:
- Product Details
Keywords
- Rapamycin
- 53123-88-9
- Sirolimus
Quick Details
- ProName: GMP certified Rapamycin Sirolimus with...
- CasNo: 53123-88-9
- Molecular Formula: C51H79NO13
- Appearance: white powder
- Application: Rapamycin is a triene macrolide antibi...
- DeliveryTime: In 5 days after payment
- PackAge: foil bag
- Port: Xiamen /Hangzhou
- ProductionCapacity: 5000 Gram/Year
- Purity: 99% up
- LimitNum: 10 Gram
- Residue on Ignition: NMT 0.5%
- Heavy Metal: NMT 0.002%
- Valid Period: 2 years
- Product name:: Rapamycin
- Other name: Sirolimus
- Purity:: 99% up
- Appearance:: White powder
- CAS No:: 53123-88-9
- Molecular Formula :: C51H79NO13
- Molecular Weight: :: 914.18
Superiority
Quick details of Rapamycin ( Sirolimus ):
Product name: Rapamycin
Other name: Sirolimus
CAS No: 53123-88-9
Molecular Formula : C51H79NO13
Molecular Weight: : 914.18
Appearance: off-white to yellow crystalline powder
Purity: 99% min
Our advantage for Rapamycin:
1) Output 5kgs/year , 500g in stock
2) Good quality ,high purity 99% up ,competitive price ,
3) with GMP /DMF documents
4) Quick delivery by courier (FedEx ,EMS ) in 3days after your payment
5) Provide free sample for testing before order
Why is SINOWAY:
1) Specialized in pharmaceutical and healthcare industrial for 37 years.
2) ISO 9001:2015 & SGS audited supplier .
3) Accept various payment terms : T.T 30-60 days.
4) We have warehouse in USA with quickly shipment .
5) We can do different terms of FOB ,CIF/CIP ,DDP ...
Details
COA of Rapamycin / Sirolimus :
|
Item |
Specifications |
Results |
|
Description |
off-white to yellow crystalline powder |
Complies |
|
Identification |
The IR spectrum of Potassium Bromide preparation of the sample exhibits maxima at the same wavelengths as that of a similar preparation of in-house reference standard |
Complies
|
|
The UV spectrum of 95% Ethanol preparation of the sample exhibits maxima at 267nm, 277nm, 288nm that of similar preparation of in-house reference standard. |
Complies |
|
|
The retention times of the peaks for the Trans- and Cis-stereoisomers in the chromatogram of Assay preparation corresponds to that in the chromatogram of the standard preparation, as obtained in the Assay |
Complies |
|
|
Loss on drying |
≤0.5% |
0.16% |
|
Heavy metal |
≤0.002% |
Complies |
|
Total impurity |
≤2.0% |
0.76% |
|
Single impurity |
≤1.0% |
0.67% |
|
Cis-stereoisomer of Sirolimus |
≤5.0% |
2.4% |
|
Assay |
≥98.0% |
99.2% |
|
Conclusion |
The production complies with enterprise standard |
|
3. Application of Rapamycin / Sirolimus :
Rapamycin is a triene macrolide antibiotic, which demonstrates
anti-fungal, anti-inflammatory, anti-tumor and immunosuppressive properties. Rapamycin has been shown to block T-cell activation and proliferation, as well as, the activation of p70 S6 kinase and exhibits strong binding to FK-506 binding proteins. Rapamycin also inhibits the activity of the protein, mTOR, (mammalian target of rapamycin) which functions in a signaling pathway to promote tumor growth. Rapamycin binds to a receptor protein (FKBP12) and the rapamycin/FKB12 complex then binds to mTOR and prevents interaction of mTOR with target proteins in this signaling pathway.
