- Product Details
Keywords
- Tenofovir Alafenamide Fumarate
- TAF
- 379270-37-8
Quick Details
- ProName: factory supply WC,DMF TAF
- CasNo: 379270-37-8
- Molecular Formula: C21H29N6O5P
- Appearance: White crystallization
- Application: Anti- Virus response
- DeliveryTime: in two weeks
- PackAge: 1kg/tin
- Port: SHANGHAI BEIJING
- ProductionCapacity: 1 Metric Ton/Day
- Purity: USP/EP/BP
- Transportation: AIR SEA TRAIN
- LimitNum: 1 Kilogram
Superiority
We are very compeitive on Tenofovir Alafenamide Fumarate.Our mfr is WC certified for this item with DMF document.
Product Name: | Tenofovir Alafenamide |
CAS: | 379270-37-8 |
MF: | C21H29N6O5P |
MW: | 476.47 |
EINECS: | 1592732-453-0 |
Product Categories: | Inhibitors;Intermediate |
Mol File: | 379270-37-8.mol |
Details
Description | Tenofovir Alafenamide (GS-7340) is a prodrug of tenofovir, which is a reverse transcriptase inhibitor, used to treat HIV and Hepatitis B.-Reverse Transcriptase inhibitor. It was developed by Gilead Sciences. Compared to tenofovir disoproxil fumarate, tenofovir alafenamide has a greater antiviral activity and better distribution into lymphoid tissues. |
Description | Tenofovir alafenamide fumarate is an oral phosphonoamidate prodrug of the reverse transcriptase inhibitor tenofovir. It was approved by the USFDA for the treatment of chronic hepatitis B virus infection with compensated liver disease. Tenofovir alafenamide fumarate was discovered and developed by Gilead as a potentially safer form of the previously approved tenofovir disoproxil fumarate (Viread). |
Definition | ChEBI: An L-alanine derivative that is isopropyl L-alaninate in which one of the amino hydrogens is replaced by an (S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)( henoxy)phosphoryl group. A prodrug for tenofovir, it is used (as the fumarate salt) in combination therapy for the treatment of HIV-1 infection. |