factory supply GMP,DMF Allopurinol CAS NO.315-30-0

We are very compeitive on Losartan potassium.Our mfr is GMP certified for this item with CEP document.

Product Name:	Allopurinol
CAS:	315-30-0
MF:	C5H4N4O
MW:	136.11
EINECS:	206-250-9
Product Categories:	Miscellaneous Natural Products;Fused Ring Systems;Heterocyclic Compounds;Antitumors for Research and Experimental Use;Chemical Reagents for Pharmacology Research;Biochemistry;PYRIMIDINE;Nucleobases and their analogs;Nucleosides, Nucleotides & Related Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Other APIs;Miscellaneous Enzyme;Bases & Related Reagents;Nucleotides;ZYLOPRIM;inhibitor
Mol File:	315-30-0.mol

Allopurinol Usage And Synthesis

Chemical Properties	White to Off-White Solid
Originator	Zyloprim ,Burroughs-Wellcome ,US ,1966
Uses	Allopurinol does not reduce serum uric acid levels by increasing renal uric acid excretion; instead it lowers plasma urate levels by inhibiting the final steps in uric acid biosynthesis. Uric acid in humans is formed primarily by xanthine oxidase-catalyzed oxidation of hypoxanthine and xanthine to uric acid. Allopurinol (8) and its primary metabolite, alloxanthine (9) [CAS: 2465-59-0], are inhibitors of xanthine oxidase. Inhibition of the last two steps in uric acid biosynthesis by blocking xanthine oxidase reduces the plasma concentration and urinary excretion of uric acid and increases the plasma levels and renal excretion of the more soluble oxypurine precursors. Normally, in humans the urinary purine content is almost solely uric acid; treatment with allopurinol results in the urinary excretion of hypoxanthine, xanthine, and uric acid, each with its independent solubility. Lowering the uric acid concentration in plasma below its limit of solubility facilitates the dissolution of uric acid deposits. The effectiveness of allopurinol in the treatment of gout and hyperuricemia that results from hematogical disorders and antineoplastic therapy has been demonstrated.
Uses	Xanthine oxidase inhibitor; decreases uric acid production. Used in treatment of hyperuricemia and chronic gout. Antiurolithic
Uses	antihyperuricemia, antigout, antiurolithic