Products Categories
    Product Certification&
    Enterprise Certification

  • Mr.Xie
    Tel: +86-592-5853819

  • Ms.Serein Yan
    Region Sales Manager
    Tel: +86 0592 5887162

  • Ms.Coco Lv
    Region Sales Manager
    Tel: 0086-592-5881075

  • Ms.Penny Pan
    Region Sales Manager
    Tel: 0086-592-5881087

  • Ms.Shirley Shi
    Region Sales Manager
    Tel: +8613666090822

  • Ms.Denise Lai
    Region Sales Manager
    Tel: 0086-592-5887167

  • Mr.Duncan Deng
    Region Sales Manager
    Tel: +8617750663255

  • Ms.Susie Yan
    Region Sales Manager
    Tel: +8618060975837

  • Ms.Annette Wang
    Region Sales Manager
    Tel: +8615882299465

  • Mobile:+86 13806035118
  • Tel:+86-592-5853819
  • Fax:+86-592-5854960
  • URL:http://www.china-sinoway.com
  • Province/state:fujian
  • City:Xiamen
  • Street:16/F,Huicheng Comm,Complex,No839 XiaHe Rd, Xiamen,China
  • MaxCard:
Home > Products >  Intermediate of Netupitant and Fosnetupitant supplier

Intermediate of Netupitant and Fosnetupitant supplier CAS NO.290297-25-5

  • msdsMSDS/COA Download

  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,T/T,Other
  • Available Specifications:

  • Product Details

Keywords

  • 290297-25-5
  • N-Methyl-4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinamine
  • Netupitant N-1

Quick Details

  • ProName: 3-PYRIDINAMINE, N-METHYL-4-(2-METHYLPH...
  • CasNo: 290297-25-5
  • Molecular Formula: C18H24N4
  • Appearance: White crystallization
  • Application: treating pulmonary embolism and preven...
  • DeliveryTime: in two weeks
  • PackAge: 25kg/drum
  • Port: SHANGHAI BEIJING
  • ProductionCapacity: 10 Metric Ton/Day
  • Purity: 99.9% by HPLC
  • Transportation: AIR SEA TRAIN
  • LimitNum: 1 Kilogram
  • Moisture Content: ≤0.5%

Superiority

We are very compeitive on Netupitant .Our mfr is Chinese GMP certified for this item with DMF/CEP document.

Product Name: 3-PYRIDINAMINE, N-METHYL-4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)-
Synonyms: 3-PYRIDINAMINE, N-METHYL-4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)-;Netupitant N-1;N-Methyl-4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinamine;N-methyl-6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-amine;methyl-[6-(4-methyl-piperazin-1-yl)-4-o-tolyl-pyridin-3-yl]-amine;N-Methyl-4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)-3-aminopyridine;Netupitant ITS-3;N-Methyl-4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinamine Oxalic acid
CAS: 290297-25-5
MF: C18H24N4
MW: 296.41
EINECS: 1592732-453-0
Product Categories:  
Mol File: 290297-25-5.mol
3-PYRIDINAMINE, N-METHYL-4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)- Structure
 
3-PYRIDINAMINE, N-METHYL-4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)- Chemical Properties
Boiling point  478.2±45.0 °C(Predicted)
density  1?+-.0.06 g/cm3(Predicted)
pka 9.73±0.38(Predicted)

Details

3-PYRIDINAMINE, N-METHYL-4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)- Usage And Synthesis
Uses N-Methyl-4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinamine is used as a reactant in the synthesis of NK1 receptor antagonists via 1,4-Grignard addition/oxidation sequence to 6-chloronicotinic acid and derivatives.
 
3-PYRIDINAMINE, N-METHYL-4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)- Preparation Products And Raw materials
Raw materials 3-PYRIDINECARBOXAMIDE, N-(1,1-DIMETHYLETHYL)-4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)--->6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-amine-->6-CHLORO-4-O-TOLYL-NICOTINAMIDE-->N-[4-iodo-6-(4-methyl-piperazin-1-yl)-pyridin-3-yl]-2,2-dimethyl-propionamide-->6-CHLORO-4-O-TOLYL-NICOTINIC ACID-->N-(6-(4-Methylpiperazin-1-yl)pyridin-3-yl)pivalaMide-->N-tert-butyl-6-chloro-4-(o-tolyl)nicotinamide-->2-(4-Methylpiperazin-1-yl)-5-nitropyridine-->O-TOLYLMAGNESIUM CHLORIDE-->Methyl (6-(4-Methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)carbaMate-->3-PYRIDINECARBOXAMIDE, 4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)--->2-Chloro-5-nitropyridine-->1-Methylpiperazine-->6-Chloronicotinic acid

Other products of this supplier

lookchemhot product CAS New CAS Cas Database Article Data Chemical Catalog