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16-beta Methyl Epoxide CAS NO.24916-90-3
- Min.Order: 0 Metric Ton
- Payment Terms: L/C,D/A,D/P,T/T
- Product Details
Keywords
- 16α-Methyl Epoxide(8-DM)
- 9b-Pregna-1,4-diene-3,20-dione,9,11b-epoxy-17,21-dihydroxy-16a-methyl- (7CI,8CI)
- 9b-Pregna-1,4-diene-3,20-dione,9,11b-epoxy-17,21-dihydroxy-16a-methyl- (7CI,8CI)
Quick Details
- ProName: 16-beta Methyl Epoxide
- CasNo: 24916-90-3
- Molecular Formula: C22H28O5
- Appearance: Almost white or white crystalline powd...
- Application: used for its anti-inflammatory and imm...
- DeliveryTime: within 7-10 days after confirm the ord...
- PackAge: 1kg/bag;25kg/drum
- Port: Shanghai/Beijing/Hangzhou
- ProductionCapacity: 1 Metric Ton/Month
- Purity: 99% up by HPLC
- Transportation: by air/sea/courier
- LimitNum: 0 Metric Ton
Superiority
1) Specialized in pharmaceutical industry since from 1987
2) ISO 9001:2015 & SGS audited supplier
3) Accept better payment terms : T.T 30-60 days.on the basic of pass SINOSURE credit investigation.
5) We have warehouse in USA with quickly shipment .
6) We can do different terms of FOB ,CIF/CIP ,DDP ...
Details
|
Product Information |
|
Product name |
Dexamethasone 9,11-epoxide/ 8-DM 16alpha-Methyl Epoxide |
|
CAS No. |
24916-90-3 |
|
Molecular Formula |
C22H28O5 |
|
Molecular Weight |
372.461 |
|
Quality Standard |
Purity: 99% up by HPLC; Any Other impurities<0.2% |
|
Appearance |
Almost white or white crystalline powder |
|
COA |
|
ANALYSIS |
SPECIFICATION |
RESULTS |
|
Appearance |
Almost white or white crystalline powder |
Almost white crystalline powder |
|
Identification(HPLC) |
The RT of the sample should be concordant with that of the working Standard |
Conforms |
|
Loss on drying |
≤0.5% |
0.19% |
|
Specific optical rotation |
Between +19° to +23° |
+20.8° |
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Related substances by HPLC |
Any other impurities ≤0.2% |
0.17% |
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Purity ≥ 99.0% |
99.2% |
|
|
Assay |
≥ 98.5% |
99.4% |
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Residual solvents |
Methanol ≤ 3000ppm |
117 ppm |
|
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Methylene chloride ≤ 1000ppm |
315 ppm |
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Conclusion |
The sample complies with the Specifications. |
|
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Usage |
Dexamethasone 9,11-epoxide is a metabolite of dexamethasone, a synthetic corticosteroid. While dexamethasone itself is widely known and used for its anti-inflammatory and immunosuppressive properties, the specific functions and properties of its metabolites, including dexamethasone 9,11-epoxide, are generally less well-documented and studied.
Here are some points about dexamethasone and its metabolites:
1. Anti-inflammatory Effects: Dexamethasone and its metabolites exert strong anti-inflammatory effects by inhibiting various inflammatory pathways. This includes reducing the production of inflammatory cytokines and inhibiting the activity of immune cells that contribute to inflammation.
2. Metabolism: When dexamethasone is administered, it undergoes metabolic transformations in the liver. One of these transformations involves the formation of dexamethasone 9,11-epoxide. This metabolite may have distinct or complementary activities compared to the parent compound.
3. Pharmacodynamics: The biological activity of dexamethasone metabolites can contribute to the overall pharmacological effects of the drug. These metabolites can potentially interact with glucocorticoid receptors or influence other molecular pathways in the body.