Intermediate of Eltrombopag ethanolamine CAS NO.18048-64-1

Product Name:	1-(3,4-DIMETHYLPHENYL)-3-METHYL-3-PYRAZOLIN-5-ONE
Synonyms:	1-(3,4-DIMETHYLPHENYL)-3-METHYL-3-PYRAZOLIN-5-ONE;3-Methyl-1-(3,4-dimethylphenyl)-2-pyrazolin-5-one;3H-Pyrazol-3-one,2-(3,4-diMethylphenyl)-2,4-dihydro-5-Methyl-;1-(3,4-diMethylphenyl)-3-Methyl-1H-pyrazol-5(4H)-one;2-(3,4-dimethylphenyl)-5-methyl-4H-pyrazol-3-one;2-(3,4-Dimethylphenyl)-2,4-dihydro-5-methyl-3H-pyrazol-3-one;1-(3,4-diMethylphenyl)-3-Methyl-3-pyrazolin-5-tone;2-Pyrazolin-5-one, 3-Methyl-1-(3,4-xylyl)-
CAS:	18048-64-1
MF:	C12H14N2O
MW:	202.25
EINECS:
Product Categories:
Mol File:	18048-64-1.mol

1-(3,4-DIMETHYLPHENYL)-3-METHYL-3-PYRAZOLIN-5-ONE Chemical Properties

Melting point	116-119℃
Boiling point	390.1±31.0 °C(Predicted)
density	1.13
storage temp.	Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Very Slightly)
pka	2.77±0.50(Predicted)
form	Solid
color	White to Off-White

Safety Information

MSDS Information

1-(3,4-DIMETHYLPHENYL)-3-METHYL-3-PYRAZOLIN-5-ONE Usage And Synthesis

Uses	1-(3,4-Dimethylphenyl)-3-methyl-1H-pyrazol-5(4H)-one is a reagent used in the enantioselective aminoalkylation of pyrazol-3-ones.

1-(3,4-DIMETHYLPHENYL)-3-METHYL-3-PYRAZOLIN-5-ONE Preparation Products And Raw materials

Raw materials	3,4-Dimethylphenylhydrazine hydrochloride-->Ethyl acetoacetate-->Methyl acetoacetate
Preparation Products	3'-[[1-(3,4-DiMethylphenyl)-1,5-dihydro-3-Methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid