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Home > Products >  Intermediate of lenalidomide 98475-07-1

Intermediate of lenalidomide 98475-07-1 CAS NO.98475-07-1

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Keywords

  • 2-(Bromomethyl)-3-nitrobenzoicacid methyl ester
  • Methyl 2-(bromomethyl)-3-nitrobenzoate
  • 98475-07-1

Quick Details

  • ProName: 2-(Bromomethyl)-3-nitrobenzoicacid met...
  • CasNo: 98475-07-1
  • Molecular Formula: C9H8BrNO4
  • Appearance: White crystallization
  • Application: Butyldimethylsilyloxyethylcarboxyet
  • DeliveryTime: in two weeks
  • PackAge: 25kg/drum
  • Port: SHANGHAI BEIJING
  • ProductionCapacity: 10 Metric Ton/Day
  • Purity: 99.9% by HPLC
  • Transportation: AIR SEA TRAIN
  • LimitNum: 1 Kilogram
  • Moisture Content: ≤0.5%

Superiority

Methyl 2-bromomethyl-3-nitrobenzoate Basic information
Product Name: Methyl 2-bromomethyl-3-nitrobenzoate
Synonyms: 2-Bromomethyl-3-NitrobenzoicAcidMethylEster;METHYL-2-BROMOMETHYL-3-NITROBENZONATE;Methyl 2-(bromomethyl)-3-nitrobenzoate 95%;Methyl 2-bromomethyl-3-nitrobenzoate;Methyl 2-bromomethyl;2-BroMoMethyl-3-nitrobenzoate Methyl ester;Benzoic acid, 2-(broMoMethyl)-3-nitro-, Methyl ester;2-Bromomethyl-3-nitro-benzoic acid
CAS: 98475-07-1
MF: C9H8BrNO4
MW: 274.07
EINECS: 619-354-8
Product Categories: Aromatics;Miscellaneous Reagents;1
Mol File: 98475-07-1.mol
Methyl 2-bromomethyl-3-nitrobenzoate Structure
 
Methyl 2-bromomethyl-3-nitrobenzoate Chemical Properties
Melting point  72-74°
Boiling point  370.9±32.0 °C(Predicted)
density  1.624±0.06 g/cm3(Predicted)
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
solubility  soluble in Methanol
form  Solid
color  White to Light yellow

Details

Safety Information
RIDADR  UN 3261 8/PG III
HazardClass  IRRITANT
HazardClass  8
PackingGroup  III
HS Code  2916310090
MSDS Information
 
Methyl 2-bromomethyl-3-nitrobenzoate Usage And Synthesis
Description Methyl 2-bromomethyl-3-nitrobenzoate is a white or light yellow solid under normal temperature and pressure. It is insoluble in water but soluble in alcoholic organic solvents. It is an organic ester derivative that can be used as an organic synthesis intermediate and a raw material for pharmaceutical chemical synthesis. It is a crucial synthesis intermediate for the drug molecule lenalidomide. Lenalidomide is an antineoplastic drug. The ester group and benzyl bromide unit in the Methyl 2-bromomethyl-3-nitrobenzoate structure are easily convertible functional groups. Its structure contains a strong electron-attracting nitro group and an easily leaving bromine atom. The nitro group is a strong electron-withdrawing group that can increase the reactivity of molecules through conjugation effects and electron attraction. Due to these properties, it has wide applications in organic synthesis transformations. 
Chemical Properties Pale Yellow Solid
 
Methyl 2-bromomethyl-3-nitrobenzoate Preparation Products And Raw materials
Raw materials Methyl 2-Methyl-4-nitrobenzoate
Preparation Products 4-AMINOISOINDOLIN-1-ONE

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