China (Mainland)
Diamondsupplier 
factory supply GMP,WC Sacubitril + Valsartan CAS NO.936623-90-4
- Min.Order: 1 Kilogram
- Payment Terms: L/C,T/T,Other
- Product Details
Keywords
- Sacubitril + Valsartan
- LCZ696
- 936623-90-4
Quick Details
- ProName: factory supply GMP,WC Sacubitril + Val...
- CasNo: 936623-90-4
- Molecular Formula: C15H18
- Appearance: White crystallization
- Application: Cardiovascular APIs,Sartan antihyperte...
- DeliveryTime: in two weeks
- PackAge: 25kg/drum
- Port: SHANGHAI BEIJING
- ProductionCapacity: 10 Metric Ton/Day
- Purity: USP/EP/BP
- Storage: room temperature
- Transportation: AIR SEA TRAIN
- LimitNum: 1 Kilogram
Superiority
We are very compeitive on Sacubitril + Valsartan.Our mfr is GMP certified for this item with WC document.
| LCZ696 , a first-in-class inhibitor of dualacting angiotensin-2 type-I receptor and neprilysin inhibitors, was developed as a molecule composed of molecular moieties of valsartan and neprilysin inhibitor prodrug AHU377 in a 1:1 ratio. Several phase 2 randomised clinical trials have been done or are underway in patients with hypertension. In a proof-of-concept randomised trial, LCZ696 was compared with valsartan in 1328 patients with mild-to-moderate hypertension, and provided fully additive reduction of blood pressure. No cases of angio-oedema were reported in the 8 week treatment period. This tolerance should be confirmed, particularly in black patients, for whom omapatrilat resulted in a higher occurrence of angio-oedema than in white patients. Indeed, in the proof-of-concept trial only about 8% of patients were black. |
Details
| Product Name: | LCZ696 |
| Synonyms: | Sacubitril mixture with Valsartan |
| CAS: | 936623-90-4 |
| MF: | C48H58N6O8 |
| MW: | 847.03 |
| Product Categories: | Cardiovascular Series;Inhibitors;API |