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Home > Products >  Imipenem intermediate KETO

Imipenem intermediate KETO CAS NO.74288-40-7

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Keywords

  • 1-Azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-(1-hydroxyethyl)-3,7-dioxo-, (4-nitrophenyl)methyl ester, [5R-[5a,6a(R*)]]-
  • KETO
  • p-Nitrobenzyl-6-(1-hydroxyethyl)-1-azabicyclo(3.2.0)heptane-3,7-dione-2-carboxylate

Quick Details

  • ProName: 1-Azabicyclo[3.2.0]heptane-2-carboxyli...
  • CasNo: 74288-40-7
  • Molecular Formula: C16H16N2O7
  • Appearance: White crystallization
  • Application: Butyldimethylsilyloxyethylcarboxyet
  • DeliveryTime: in two weeks
  • PackAge: 25kg/drum
  • Port: SHANGHAI BEIJING
  • ProductionCapacity: 10 Metric Ton/Day
  • Purity: 99.9% by HPLC
  • Transportation: AIR SEA TRAIN
  • LimitNum: 1 Kilogram
  • Moisture Content: ≤0.5%

Superiority

Product Name: p-Nitrobenzyl-6-(1-hydroxyethyl)-1-azabicyclo(3.2.0)heptane-3,7-dione-2-carboxylate
Synonyms: INTERMEDIANTE FOR IMIPENEM;adc 13;6-[(1R)-1-Hydroxyethyl]-3,7-dioxo-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (5R,6S)-(4-nitrophenyl)methyl ester;4-NITROBENZYL (5R,6S)-6-[(1R)-1-HYDROXYETHYL]-3,7-DIOXO-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLATE;1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, 6-[(1R)-1-HYDROXYETHYL]-3,7-DIOXO-, (4-NITROPHENYL)METHYL ESTER, (5R,6S)-;P-NITROBENZYL-6-(1-HYDROXYETHYL)-1-AZABICYCLO(3.2.0) HEPTANE-3,7-DIONE-2-CARBOXYLATE;6-(1-Hydroxy-ethyl)-3,7-dioxo-1-aza-bicyclo(3.2.0)heptane-2-carboxylic Acid 4-Nitro-benzyl Ester;(5R,6S)-6[(1R)-1-hydroxyethyl]-1-azabicyclo[3.2.0]-heptan-3,7-dione-2-carboxylic acid-p-nitro benzyl ester
CAS: 74288-40-7
MF: C16H16N2O7
MW: 348.31
EINECS: 616-072-7
Product Categories: (intermediate of imipenem,panipenem);Intermediates & Fine Chemicals;Pharmaceuticals
Mol File: 74288-40-7.mol
p-Nitrobenzyl-6-(1-hydroxyethyl)-1-azabicyclo(3.2.0)heptane-3,7-dione-2-carboxylate Structure

Details

p-Nitrobenzyl-6-(1-hydroxyethyl)-1-azabicyclo(3.2.0)heptane-3,7-dione-2-carboxylate Chemical Properties
Melting point  108-110°C
Boiling point  601.3±55.0 °C(Predicted)
density  1.50±0.1 g/cm3(Predicted)
storage temp.  2-8°C Refrigerator
solubility  Chloroform (Slightly), Methanol (Slightly)
form  Solid
pka 11.26±0.40(Predicted)
color  White to Pale Beige
CAS DataBase Reference 74288-40-7(CAS DataBase Reference)
 
Safety Information
MSDS Information
 
p-Nitrobenzyl-6-(1-hydroxyethyl)-1-azabicyclo(3.2.0)heptane-3,7-dione-2-carboxylate Usage And Synthesis
Chemical Properties White to Off-White Powder
Uses Imipenem intermediate.
Application intermediate in orgaic syntheses
storage sealed in dry, store in freezer, under -20°C
 
p-Nitrobenzyl-6-(1-hydroxyethyl)-1-azabicyclo(3.2.0)heptane-3,7-dione-2-carboxylate Preparation Products And Raw materials
Raw materials 2-Azetidinebutanoic acid, a-diazo-3-(1-hydroxyethyl)-b,4-dioxo-, (4-nitrophenyl)Methyl ester, [2R-[2a,3b(R*)]]-

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