factory supply GMP,DMF Tiapride hydrochloride CAS NO.51012-32-9

We are very compeitive on Tiapride HCL.Our mfr is GMP certified for this item with DMF document.

Product Name:	Tiapride
Synonyms:	TIAPRIDE;Tiapride hcl;N-[2-Diethylamino ethyl]-5-[methylsufonyl]-o-anisamide;Cyclovirobune D;N-(2-Diethylaminoethyl)-2-methoxy-5-methylsulfonylbenzamide;N-[2-(Ethylamino)ethyl]-2-methoxy-5-(methylsulfonyl)benzamide;N-[2-(Diethylamino)ethyl]-5-(methylsulfonyl)-2-methoxybenzamide;N-[2-(Diethylamino)ethyl]-5-mesyl-2-methoxybenzamide
CAS:	51012-32-9
MF:	C15H24N2O4S
MW:	328.43
EINECS:	256-907-9
Product Categories:	Dopamine receptor;NATURETIN;Active Pharmaceutical Ingredients
Mol File:	51012-32-9.mol

Tiapride Usage And Synthesis

Originator	Tiapridal,Delagrange,France,1977
Uses	diuretic, antihypertensive
Uses	Tiapride hydrochloride is a D2DR and D3DR inhibitor; Anti-psychotic agent and alternative treatment for Tourette’s syndrome.
Manufacturing Process	5 g of 2-methoxy-5-methylsulfonylbenzoic acid, 50 ml of dioxan, 3.02 ml of triethylamine and 3 g of isobutyl chloroformate were introduced into a 250 ml balloon flask at ambient temperature. After the mixture had been stirred for 30 minutes, 3 g of N,N_x0002_diethylethylenediamine were added. The reaction mixture was stirred for 6 hours and the solvents were evaporated under vacuum. The residue was dissolved in 50 ml of water and the solution was made alkaline with sodium hydroxide. The precipitate formed was filtered, washed and dried in a drying oven at 60°C. 6 g of N-(diethylaminoethyl)-2-methoxy- 5-methylsulfonylbenzamide (melting point: 124°C to 125°C) was produced.