China (Mainland)
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High Quality 99% Sitagliptin phosphate monohydrate CAS NO.486460-32-6
- FOB Price: USD: 25.00-800.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,Other
- Available Specifications:
Medicine Grade(1-99)KilogramMedicine Grade(100-1000)Kilogram
- Product Details
Keywords
- Sitagliptin Powder
- factory price
- High purity 99%
Quick Details
- ProName: High Quality 99% Sitagliptin phosphate...
- CasNo: 486460-32-6
- Molecular Formula: C16H20F6N5O6P
- Appearance: White powder
- Application: Sitagliptin is a trizolopyrazine dipep...
- DeliveryTime: in 7 days afte your payment ( in stock...
- PackAge: 1kg/bag ;5kg/drum:25KG/drum
- Port: any port in China
- ProductionCapacity: 20 Metric Ton/Month
- Purity: 99% up
- Storage: in low tempreture
- Transportation: in low tempreture
- LimitNum: 1 Kilogram
Superiority
Why is SINOWAY:
1) Specialized in pharmaceutical and healthcare industrial for 34 years.
2) ISO 9001:2015 & SGS audited supplier .
3) Accept various payment terms : T.T 30-60 days.
4) We have warehouse in USA with quickly shipment .
5) We can do different terms of FOB ,CIF/CIP ,DDP ...
Why choose us
1. best quality in your requirement
2. competitive price in china market
3. mature technical support
4. professional logistic support
5. full experience of large numbers containers loading in chinese sea port
6. fast shipment by reputed shipping line
7. packing with pallet as buyer's special request
8. best service after shipment with email !
9. cargoes together with container after-sales service available
10. full experience in export
11. raw materials from chinese origin
Details
Product Information
| product Name | Sitagliptin |
|---|---|
| Molecular Formula | C16H15F6N5O |
| Molecular Weight | 407.3136 |
| InChI | InChI=1/C16H15F6N5O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/m0/s1 |
| CAS Registry Number | 486460-32-6;790712-60-6 |
| Molecular Structure |
|
| Density | 1.614g/cm3 |
| Boiling point | 529.905°C at 760 mmHg |
| Refractive index | 1.59 |
| Flash point | 274.277°C |
| Vapour Pressur | 0mmHg at 25°C |
Function
Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.
Application
An anti-diabetic (antihyperglycemic) drug of the dipeptidyl peptidase-4 (DPP-4) class. Inhibition of the enzyme DPP-4 is thought to increase Glucagon-like peptide-1 (GLP-1) which inhibits glucagon release , stimulates the insulin release and lowers blood glucose.
Sitagliptin phosphate monohydrate should not be used in patients with type 1 diabetes or for the treatment of diabetic ketoacidosis, as it would not be effective in these settings.
Sitagliptin phosphate monohydratehas not been studied in patients with a history of pancreatitis. It is unknown whether patients with a history of pancreatitis are at increased risk for the development of pancreatitis while using Sitagliptin phosphate monohydrate.
Specification
|
Appearance |
White or almost White powder |
White powder |
|
Solubility |
Easy to dissolve in the water |
Complies |
|
Identification |
High -performance liquid chromatograph HPLC |
Almost the same |
|
Infrared absorption |
Almost the same |
|
|
Melting point |
203.0-205.0ºC |
204.0~205.0ºC |
|
Chiral impurity: |
≤1.0% |
0.4%
|
|
Related Impurities: |
Total Impurities ≤1.0% |
0.63% |
|
Water |
≤1.0% |
0.6% |
|
Heavy metals |
≤20ppm |
<20ppm |
|
Residue on ignition |
≤0.1% |
0.01 % |
|
Specific Rotation |
Between -18.0 °and 23.0° |
-21.05° |
|
HPLC Assay |
98.0% ~ 102.0% |
99.5% |