Micafungin 208538-73-2 CAS NO.208538-73-2

Product Name:	Micafungin sodium
Synonyms:	Micafungin sodium;1-[(4R,5R)-4,5-Dihydroxy-N2-[4-[5-[4-(pentyloxy)phenyl]-3-isoxazolyl]benzoyl]-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneuMocandin A0 MonosodiuM Salt;Funguard;Micafungin SodiuM(FK-463, MycaMine);Mycamine;CS-705;FK 463; FUNGUARD; MYCAMINE;micafungin sodium Impurity
CAS:	208538-73-2
MF:	C56H72N9NaO23S
MW:	1294.28
EINECS:	810-840-7
Product Categories:	Inhibitors;API
Mol File:	208538-73-2.mol

Micafungin sodium Chemical Properties

Melting point	>180°C (dec.)
storage temp.	Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility	DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated)
form	Solid
color	White to Off-White
Stability:	Hygroscopic
CAS DataBase Reference	208538-73-2

Description	The semi-synthetic echinocandin antifungal agent, micafungin sodium (15), is a 1,3-β-glucan synthase inhibitor discovered by Fujisawa. It is for the treatment and prevention of infections caused by Aspergillus and Candida such as fungemia, respiratory mycosis and gastrointestinal mycosis.
Chemical Properties	Off-White Solid
Uses	An echinocandin antifungal drug which inhibits the synthesis of 1,3-β-D-glucan, an essential component of the fungal cell wall, and represent a valuable treatment option for fungal infections.
Uses	Micafungin sodium is the salt of the semi-synthetic cyclic lipopeptide, micafungin, a member of the echinocandin class that was reported in 1999 from Fujisawa in Japan. The sodium salt takes advantage of the aryl sulphate moiety providing improved water solubility and is the preferred salt for pharmaceutical applications. Like all echinocandins, micafungin inhibits the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi.
Uses	Micafungin is an echinocandin antifungal that inhibits 1,3-β-D-glucan synthesis. It has fungicidal activity against virtually all species of Candida, including those resistant to fluconazole, and is fungistatic against Aspergillus spp.[Cayman Chemical]