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Home > Products >  Factory Supply Raw Material Lopinavir Powder

Factory Supply Raw Material Lopinavir Powder CAS NO.192725-17-0

  • FOB Price: USD: 10.00-1,350.00 /Kilogram Get Latest Price
  • Min.Order: 1 Metric Ton
  • Payment Terms: L/C,D/A,D/P,T/T,Other
  • Available Specifications:

    Medicine Grade(1-99)KilogramMedicine Grade(100-1000)Kilogram

  • Product Details

Keywords

  • Lopinavir
  • factory price
  • High purity 99%

Quick Details

  • ProName: Factory Supply Raw Material Lopinavir ...
  • CasNo: 192725-17-0
  • Molecular Formula: C37H48N4O5
  • Appearance: White powder
  • Application: Lopinavir is used in combination with ...
  • DeliveryTime: in 7 days afte your payment ( in stock...
  • PackAge: 1kg/bag ;5kg/drum:25KG/drum
  • Port: any port in China
  • ProductionCapacity: 20 Metric Ton/Month
  • Purity: 99% up
  • Storage: in low tempreture
  • Transportation: in low tempreture
  • LimitNum: 1 Metric Ton

Superiority

Why is SINOWAY:

1) Specialized in pharmaceutical and healthcare industrial for 34 years.

2) ISO 9001:2015 & SGS audited supplier . 

3) Accept various payment terms : T.T 30-60 days.

4) We have warehouse in USA with quickly shipment .

5) We can do different terms of FOB ,CIF/CIP ,DDP ...

Why choose us

1. best quality in your requirement
2. competitive price in china market
3. mature technical support
4. professional logistic support
5. full experience of large numbers containers loading in chinese sea port
6. fast shipment by reputed shipping line
7. packing with pallet as buyer's special request
8. best service after shipment with email !
9. cargoes together with container after-sales service available
10. full experience in export
11. raw materials from chinese origin

Details

Product Information

Product name                                              

Lopinavir                                                                                    

CAS No.

192725-17-0

Molecular Formula

C37H48N4O5

Molecular Weight

628.801

Quality Standard

99% up, USP42, Medicine Grade

Appearance

White powder

COA

TEST

SPECIFICATION                        

RESULTS                                                   

Description

White  powder

Complies

Identification

IR

Complies

 

HPLC

Complies 

Heavy metal

≤10ppm

5ppm

Pb

≤3ppm

1.5ppm

Hg

≤0.1ppm

0.05ppm

Cd

≤1ppm

0.2ppm

Loss on drying

≤0.5%

0.12

Residue on lgnition                      

≤0.1%

0.03

Single impurity

≤0.5%

0.12

Total impurity

≤1.0%

0.29

Total bacteria

≤1000cfu/g

<1000

Yeast and Mould

≤100 cfu/g

<000

E.coli/25g

Absent

Absent

Salmonella/25g

Absent

Absent

Assay

≥99.0%

99.4%

Conclusion

Conforms with USP/EP standards

Usage

Function of Lopinavir

Lopinavir is used in combination with other antiretroviral drugs to treat human immunodeficiency virus-1 (HIV-1) infection in adults and children over 2 years old.

Lopinavir is an HIV protease inhibitor, which can block the division of Gag-Pol polyprotein, resulting in the production of immature, non-infectious virus particles; ritonavir is a kind of HIV-1 and HIV- 2 Peptidomimetic inhibitors of aspartyl protease activity. By inhibiting HIV protease, the enzyme cannot process the precursor of Gag-Pol polyprotein, resulting in the formation of immature HIV particles, which prevents the start of a new infection cycle. Ritonavir can inhibit CYP3A-mediated metabolism of lopinavir, resulting in a higher concentration of lopinavir.

Antiviral activity of Lopinavir: In vitro antiviral drug activity studies in combination with lopinavir have shown that the combination of lopinavir and nelfinavir will increase the antagonistic effect, and it can be compared with amprenavir, atazanavir and indinavir The combined application of Vivi, Saquinavir and Telanavir will increase the synergy. The EC50 value of lopinavir for three different HIV-2 virus strains is between 12~180nM (0.008~113 μg/mL).

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