China (Mainland)
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Factory Supply Raw Material Lopinavir Powder CAS NO.192725-17-0
- FOB Price: USD: 10.00-1,350.00 /Kilogram Get Latest Price
- Min.Order: 1 Metric Ton
- Payment Terms: L/C,D/A,D/P,T/T,Other
- Available Specifications:
Medicine Grade(1-99)KilogramMedicine Grade(100-1000)Kilogram
- Product Details
Keywords
- Lopinavir
- factory price
- High purity 99%
Quick Details
- ProName: Factory Supply Raw Material Lopinavir ...
- CasNo: 192725-17-0
- Molecular Formula: C37H48N4O5
- Appearance: White powder
- Application: Lopinavir is used in combination with ...
- DeliveryTime: in 7 days afte your payment ( in stock...
- PackAge: 1kg/bag ;5kg/drum:25KG/drum
- Port: any port in China
- ProductionCapacity: 20 Metric Ton/Month
- Purity: 99% up
- Storage: in low tempreture
- Transportation: in low tempreture
- LimitNum: 1 Metric Ton
Superiority
Why is SINOWAY:
1) Specialized in pharmaceutical and healthcare industrial for 34 years.
2) ISO 9001:2015 & SGS audited supplier .
3) Accept various payment terms : T.T 30-60 days.
4) We have warehouse in USA with quickly shipment .
5) We can do different terms of FOB ,CIF/CIP ,DDP ...
Why choose us
1. best quality in your requirement
2. competitive price in china market
3. mature technical support
4. professional logistic support
5. full experience of large numbers containers loading in chinese sea port
6. fast shipment by reputed shipping line
7. packing with pallet as buyer's special request
8. best service after shipment with email !
9. cargoes together with container after-sales service available
10. full experience in export
11. raw materials from chinese origin
Details
Product Information
|
Product name |
Lopinavir |
|
CAS No. |
192725-17-0 |
|
Molecular Formula |
C37H48N4O5 |
|
Molecular Weight |
628.801 |
|
Quality Standard |
99% up, USP42, Medicine Grade |
|
Appearance |
White powder |
COA
|
TEST |
SPECIFICATION |
RESULTS |
|
Description |
White powder |
Complies |
|
Identification |
IR |
Complies |
|
|
HPLC |
Complies |
|
Heavy metal |
≤10ppm |
5ppm |
|
Pb |
≤3ppm |
1.5ppm |
|
Hg |
≤0.1ppm |
0.05ppm |
|
Cd |
≤1ppm |
0.2ppm |
|
Loss on drying |
≤0.5% |
0.12 |
|
Residue on lgnition |
≤0.1% |
0.03 |
|
Single impurity |
≤0.5% |
0.12 |
|
Total impurity |
≤1.0% |
0.29 |
|
Total bacteria |
≤1000cfu/g |
<1000 |
|
Yeast and Mould |
≤100 cfu/g |
<000 |
|
E.coli/25g |
Absent |
Absent |
|
Salmonella/25g |
Absent |
Absent |
|
Assay |
≥99.0% |
99.4% |
|
Conclusion |
Conforms with USP/EP standards |
|
Usage
Function of Lopinavir
Lopinavir is used in combination with other antiretroviral drugs to treat human immunodeficiency virus-1 (HIV-1) infection in adults and children over 2 years old.
Lopinavir is an HIV protease inhibitor, which can block the division of Gag-Pol polyprotein, resulting in the production of immature, non-infectious virus particles; ritonavir is a kind of HIV-1 and HIV- 2 Peptidomimetic inhibitors of aspartyl protease activity. By inhibiting HIV protease, the enzyme cannot process the precursor of Gag-Pol polyprotein, resulting in the formation of immature HIV particles, which prevents the start of a new infection cycle. Ritonavir can inhibit CYP3A-mediated metabolism of lopinavir, resulting in a higher concentration of lopinavir.
Antiviral activity of Lopinavir: In vitro antiviral drug activity studies in combination with lopinavir have shown that the combination of lopinavir and nelfinavir will increase the antagonistic effect, and it can be compared with amprenavir, atazanavir and indinavir The combined application of Vivi, Saquinavir and Telanavir will increase the synergy. The EC50 value of lopinavir for three different HIV-2 virus strains is between 12~180nM (0.008~113 μg/mL).
