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Polymyxin B Sulphate CAS:1405-20-5 CAS NO.1405-20-5
- Min.Order: 25 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,Other
- Product Details
Keywords
- Polymyxin B Sulphate CAS:1405-20-5
- API powder Polymyxin B Sulphate
- Polymyxin B Sulphate CAS:1405-20-5
Quick Details
- ProName: Polymyxin B Sulphate CAS:1405-20-5
- CasNo: 1405-20-5
- Molecular Formula: C56H100N16O17S
- Appearance: WHITE TO ALMOST WHITE POWDER, HYGROSCO...
- DeliveryTime: within 7-10 days after order
- PackAge: 25kg/drum or per customer's requiremen...
- Port: Beijing/Shanghai/Hangzhou/Shenzhen
- ProductionCapacity: 1000 Kilogram/Month
- Purity: NOT?LESS?THAN?6500IU/MG
- Transportation: by air. by sea or courier
- LimitNum: 25 Kilogram
- Heavy Metal: NOT?MORE?THAN?20PPM
- Valid Period: 2 years
- LOSS?ON?DRYING: NOT?MORE?THAN?7.0%
- SULPHATED?ASH: NOT?MORE?THAN?0.75%
Superiority
1) Specialized in pharmaceutical industry since from 1987
2) ISO 9001:2015 & SGS audited supplier
3) Accept better payment terms : T.T 30-60 days.on the basic of pass SINOSURE credit investigation.
5) We have warehouse in USA with quickly shipment .
6) We can do different terms of FOB ,CIF/CIP ,DDP ...
Details
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Company Information |
Sinoway Industrial co., ltd. was established in 1987 in Xiamen, China, and now has been a leading group specialized in research, development, custom manufacturing and trading of pharmaceutical intermediates, APIs, health and food supplements, cosmetic raw materials, herbal extracts, polypeptides and prostaglandin derivatives, etc..
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Product Information |
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Product name |
Polymyxin B Sulphate |
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CAS No. |
1405-20-5 |
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Molecular Formula |
C56H100N16O17S |
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Molecular Weight |
1301.56 |
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Quality Standard |
6500IU/MG up /Medicine Grade |
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Appearance |
White powder |
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COA of Polymyxin B Sulphate |
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ITEMS |
SPECIFICATION |
RESULTS |
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DESCRIPTION |
WHITE TO ALMOST WHITE POWDER, HYGROSCOPIC. |
CONFORMS |
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SOLUBILITY |
FREELY SOLUBLE IN WATER; SLIGHTLY SOLUBLE IN ALCOHOL. |
CONFORMS |
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IDENTIFICATION |
A. LIQUID CHROMATOGRAPHIC IDENTIFICATION TEST B. A REDDISH VIOLET COLOR IS PRODUCED C. TEST FOR SULFATE |
CONFORMS |
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PH(2%) |
5.0~7.0 |
5.7 |
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PH(0.5%) |
5.0~7.5 |
5.5 |
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SPECIFIC ROTATION |
-78°- -90° |
-80.0° |
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LOSS ON DRYING |
NOT MORE THAN 7.0% |
4.7% |
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PHENYLALANINE |
9.0%~12.0% |
10.31% |
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SULPHATED ASH |
NOT MORE THAN 0.75% |
0.31% |
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SULPHATE |
15.5%~17.5% |
16.53% |
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HEAVY METALS |
NOT MORE THAN 20PPM |
<20PPM |
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ASSAY(MICROBIAL) (ON DRIED BASIS) |
NOT LESS THAN 6500IU/MG |
8220 IU/MG |
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PARTICLE SIZE |
99.0%:NOT MORE THAN 30UM BY VOL. 90.0%:NOT MORE THAN 25UM BY VOL. 75.0%:NOT MORE THAN 20UM BY VOL. MEAN DIAMETER:NOT MORE THAN 8.0UM |
CONFORMS |
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CONCLUSION:THE RESULTS CONFORM TO THE STANDARD OF USP34 |
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Usage |
Function of Polymyxin B Sulphate
Polymyxin B sulphate is similar to polymyxin E. It can inhibit gram-negative bacilli such as Escherichia coli, Pseudomonas aeruginosa, Para Escherichia coli, Klebsiella pneumoniae, Acidophilus, Pertussis and Shigella, etc. Or bactericidal effect. It is mainly used for Pseudomonas aeruginosa and other Pseudomonas to cause the wounds, urinary tract, eyes, ears, trachea and other parts of the Chemicalbook infection. It can also be used for sepsis and peritonitis. And resistant to aminoglycosides, resistant to third-generation cephalosporin bacteria and Pseudomonas aeruginosa or other sensitive bacteria caused by serious infections, such as bacteremia, endocarditis, pneumonia, post-burn infections, etc.
Polymyxin B is a peptide antibiotic against gram-negative bacilli, which can change the membrane structure to leak small molecules and inhibit the growth of gram-negative bacteria. Has a bactericidal effect on E. coli Chemicalbook. Binds to the lipid A portion of bacterial lipopolysaccharides. Inducing small holes in the outer cell membrane. Mode of action: Combine and interfere with the permeability of the cell plasma membrane. Antibacterial spectrum: Gram-negative bacteria.
