factory supply GMP,DMF Sulfadimethoxine CAS NO.1405-10-3

We are very compeitive on Sulfadimethoxine.Our mfr is GMP certified for this item with DMF document.

Product Name:	Sulfadimethoxine
Synonyms:	deposul;diasulfa;madroxin;madroxine;maxulvet;memcozine;metoxidon;n(sup1)-(2,6-dimethoxy-4-pyrimidinyl)-sulfanilamid
CAS:	122-11-2
MF:	C12H14N4O4S
MW:	310.33
EINECS:	204-523-7
Product Categories:	MADRIBON;APIs;Antibiotics for Research and Experimental Use;Biochemistry;Sulfonamides (Antibiotics for Research and Experimental Use);Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
Mol File:	122-11-2.mol

Sulfadimethoxine Usage And Synthesis

Chemical Properties	White Solid
Originator	Madribon,Roche,US,1958
Uses	Antibacterial.
Definition	ChEBI: A sulfonamide consisting of pyrimidine having methoxy substituents at the 2- and 6-positions and a 4-aminobenzenesulfonamido group at the 4-position.
Manufacturing Process	1.4 g of 4-phenylsulfonyl-2,6-dimethoxypyrimidine and 4 g of sodium sulfanilamide (both dried over potassium hydroxide) were very finely ground and heated in an oil bath for 10 hours at 120°C (inside temperature). The reaction mixture was taken up in 30 ml of water and treated with 3 ml of 2 N sodium hydroxide solution. After standing for one hour at 0°C, the turbid solution was filtered and the filtrate was made alkaline with sodium carbonate. After again standing for one hour at 0°C, the precipitate was filtered off (1.9 g of regenerated sulfanilamide) and the filtrate was neutralized with acetic acid, whereupon crystallization resulted. The isolated crystals of 4-sulfanilamido- 2,6-dimethoxypyrimidine weighed 1.3 g (84% of theory), melting point 190°C to 196°C.
Therapeutic Function	Antibacterial