factory supply GMP,DMF,CEP Neomycin sulfate CAS NO.1405-10-3

We are very compeitive on Neomycin sulfate.Our mfr is GMP certified for this item with CEP document.

Product Name:	Neomycin sulfate
CAS:	1405-10-3
MF:	C23H48N6O17S
MW:	712.72
EINECS:	215-773-1
Product Categories:	13C & 2H Sugars;Aminoglycosides (Antibiotics for Research and Experimental Use);Antibiotics for Research and Experimental Use;Biochemistry;Antibiotic Explorer;Carbohydrates & Derivatives;AminoglycosidesAlphabetic;Antibiotics;Chemical Structure;N;NA - NI;AminoglycosidesAntibiotics;Antibacterial;Peptide Synthesis/Antibiotics;Antibiotics A to;Antibiotics by Application;Antibiotics N-SAntibiotics;Antineoplastic and Immunosuppressive AntibioticsAntibiotics;Chemical Structure Class;Genetic Marker SelectionAntibiotics;Interferes with Protein SynthesisSpectrum of Activity;L - ZMore...Close...;Mechanism of Action;API's;MYCIFRADIN;antibiotic;Antimicrobial;API

Neomycin sulfate Chemical Properties

Melting point	>187°C (dec.)
alpha	D20 +54° (c = 2 in H2O)
refractive index	56 ° (C=10, H2O)
Fp	56℃
storage temp.	2-8°C
solubility	H₂O: 50 mg/mL As a stock solution. Stock solutions should be filter sterilized and stored at 2-8°C. Stable at 37°C for 5 days.
form	powder
color	white to slightly yellow
PH	5.0-7.5 (50g/l, H2O, 20℃)
Water Solubility	Soluble in water
Merck	14,6454
Stability:	Stable. Incompatible with strong oxidizing agents.
InChIKey	OIXVKQDWLFHVGR-VTSVPHRWSA-N
CAS DataBase Reference	1405-10-3(CAS DataBase Reference)
EPA Substance Registry System	Neomycin sulfate (1405-10-3)

Neomycin sulfate Usage And Synthesis

Chemical Properties	NEOMYCIN SULFATE is white or yellowish-white powder, hygroscopic.
Uses	NEOMYCIN SULFATE is an aminoglycoside antibiotic found in many topical medications. NEOMYCIN SULFATE has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia.
Uses	NEOMYCIN SULFATE is an aminoglycoside antibiotic produced by S. fradiae that inhibits protein translation by binding to the small subunit of prokaryotic ribosomes. It blocks voltage-sensitive Ca2+ channels and is a potent inhibitor of skeletal muscle sarcoplasmic reticulum Ca2+ release. NEOMYCIN SULFATE has been shown to inhibit inositol phospholipid turnover, phospholipase C, and phosphatidylcholine-phospholipase D activity (IC50 = 65 μM). It is highly effective against Gram-positive and Gram-negative bacteria and is commonly used for the prevention of bacterial contamination of cell cultures.
Uses	Neomycin sulfate is an antibiotic (can be used effectively against most bacteria that cause skin, eye and outer ear infections); broad-spectrum antibiotic in topical creams, powders, ointments, eye and ear drops; systemic antibiotic and growth promotor in veterinary use.