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Home > Products >  factory supply GMP,DMF,CEP Spiramycin

factory supply GMP,DMF,CEP Spiramycin CAS NO.8025-81-8

  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,T/T,Other
  • Product Details

Keywords

  • Spiramycin
  • foromacidin
  • 8025-81-8

Quick Details

  • ProName: factory supply GMP,DMF,CEP Spiramycin
  • CasNo: 8025-81-8
  • Molecular Formula: C22H23ClKN6O
  • Appearance: White crystallization
  • Application: Cardiovascular APIs,Sartan antihyperte...
  • DeliveryTime: in two weeks
  • PackAge: 25kg/drum
  • Port: SHANGHAI BEIJING
  • ProductionCapacity: 10 Metric Ton/Day
  • Purity: USP/EP/BP
  • Storage: room temperature
  • Transportation: AIR SEA TRAIN
  • LimitNum: 1 Kilogram

Details

Spiramycin Chemical Properties
Melting point  126-128 °C
alpha  D20 -80° (methanol)
Boiling point  914℃
refractive index  81 ° (C=2, 10% AcOH)
Fp  >110°(230°F)
storage temp.  2-8°C
solubility  ethanol: 50 mg/mL, clear to slightly hazy, light-yellow
form  powder
color  white to light yellow
optical activity [α]/D -85 to -80° in water (Specific rotation (dry basis))
Water Solubility  Soluble in methanol. Slightly soluble in water
Merck  14,8752
CAS DataBase Reference 8025-81-8
Uses Spiramycin I (foromacidin A) is the major analogue of a complex of 16-membered macrocyclic lactones produced by S. ambofaciens and S. spiramyceticus that have broad spectrum antibiotic activity. Spiramycins are unusual among the macrocyclic lactones in that they contain two basic sugars. Spiramycin complex has been used in both human and animal health but its use has not been widespread.
Manufacturing Process The process for producing spiramycin comprises inoculating an aqueous nutrient medium with a culture of the NRRL No. 2420, allowing aerobic fermentation to take place and separating from the culture medium the spiramycin thus formed. The culture medium also contains the antibiotic substance known as Congocidin which, however, does not possess the same useful properties as spiramycin and which can be isolated in crystalline form. The separation of the two antibiotic substances is readily achieved.
 

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