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Home > Products >  99% up by HPLC Nilotinib 641571-10-0

99% up by HPLC Nilotinib 641571-10-0 CAS NO.641571-10-0

  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T
  • Product Details

Keywords

  • Nilotinib 641571-10-0
  • Nilotinib
  • 641571-10-0

Quick Details

  • ProName: 99% up by HPLC Nilotinib 641571-10-0
  • CasNo: 641571-10-0
  • Molecular Formula: C28H22F3N7O
  • Appearance: White or almost white hygroscopic powd...
  • Application: API
  • DeliveryTime: 7 working days
  • PackAge: 25kg per drum
  • Port: shanghai/beijing/hangzhou
  • ProductionCapacity: 1000 Kilogram/Month
  • Purity: 99.9%
  • Storage: Normal temperature
  • Transportation: normal temperature.
  • LimitNum: 1 Kilogram

Superiority

Why is SINOWAY:

1) Specialized in pharmaceutical and healthcare industrial for 34 years.

2) ISO 9001:2015 & SGS audited supplier . 

3) Accept various payment terms : T.T 30-60 days.

4) We have warehouse in USA with quickly shipment .

5) We can do different terms of FOB ,CIF/CIP ,DDP ...

 

Details

Product name

Nilotinib

CAS No.

641571-10-0

Molecular Formula

C28H22F3N7O

Molecular Weight

529.523

Quality Standard

99% up by HPLC

Appearance

White to pale yellow powder

 

Function of Nilotinib

Nilotinib is improved from the molecular structure of imatinib, and has stronger selectivity for BCR-ABL kinase activity, and its inhibitory effect on tyrosine kinase is 30 times stronger than that of imatinib, which can inhibit Kinase activity of imatinib-resistant BCR-ABL mutants, while also inhibiting KIT and PDGFR kinase activities. For the treatment of chronic myeloid leukemia (CML), a life-threatening blood cancer that is refractory to or intolerable to imatinib mesylate. Based on a pivotal Phase II clinical study design evaluating the positive results of oral nilotinib in clinical trials against imatinib mesylate or in patients with Ph+ CML in the slow and accelerated phases of apparent toxicity: High efficacy, good tolerance, and manageable safety.

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