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Home > Products >  factory supply GMP,DMF Tenofovir Disoproxil Fumarate

factory supply GMP,DMF Tenofovir Disoproxil Fumarate CAS NO.202138-50-9

  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,T/T,Other
  • Product Details

Keywords

  • Tenofovir Disoproxil Fumarate
  • TDF
  • 202138-50-9

Quick Details

  • ProName: factory supply GMP,DMF Tenofovir Disop...
  • CasNo: 202138-50-9
  • Molecular Formula: C23H34N5O14P
  • Appearance: White crystallization
  • Application: anti- Virus response
  • DeliveryTime: in two weeks
  • PackAge: 1kg/tin
  • Port: SHANGHAI BEIJING
  • ProductionCapacity: 1 Metric Ton/Day
  • Purity: USP/EP/BP
  • Transportation: AIR SEA TRAIN
  • LimitNum: 1 Kilogram

Superiority

We are very compeitive on Tenofovir Disoproxil Fumarate.Our mfr is GMP certified for this item with DMF document. 

Product Name: Tenofovir disoproxil fumarate
Synonyms: TDF
CAS: 202138-50-9
MF: C23H34N5O14P
MW: 635.52
EINECS: 687-766-5
Product Categories: Bases & Related Reagents;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Phosphorylating and Phosphitylating Agents;Inhibitors;Tenofovir;API
Mol File: 202138-50-9.mol

Details

Overview Tenofovir disoproxil fumarate, a prodrug of tenofovir[Trade name: “Viread”] developed by Gilead Sciences, is a kind of nucleotide-analogues antiretroviral drugs, taking effect through acting as the reverse transcriptase inhibitors[nRTIs], which block reverse transcriptase, an enzyme crucial to viral production in HIV-infected people[1-4]. It should be noted that it is the first nucleotide reverse transcriptase inhibitor that has ever used for the treatment of HIV infection[5]. Tenofovir disoproxil fumarate is converted to tenofovir in vivo, which is an acyclic nucleoside phosphonate[nucleotide] analog of adenosine 5'-monophosphate[5,6]. It is generally used in combination with other kinds of medicine. HIV medicines can't cure HIV/AIDS, but taking a combination of HIV medicines[called an HIV regimen] every day can help people with HIV live longer, healthier lives[7]. Based on the FDA document, tenofovir disoproxil fumarate can also be for the treatment of chronic hepatitis B virus[HBV] infection in adults and children 12 years of age and older[1,3, 4, 8].
Indication and application Tenofovir disoproxil fumarate[trade name: Viread®], an antiviral drug, is indicated as the treatment for both HIV and Hepatitis B virus[HBV]. Viread® is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients 2 years of age and older. It is also indicated for the treatment of chronic hepatitis B in adults and pediatric patients 12 years of age and older

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