China (Mainland)
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high quality 99% up EDMF Febuxostat 144060-53-7 CAS NO.144060-53-7
- FOB Price: USD: 10,000.00-10,000.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: T/T
- Available Specifications:
99% up(1-100)Kilogram
- Product Details
Keywords
- Febuxostat Intermediate
- 144060-53-7
- Febuxostat
Quick Details
- ProName: high quality 99% up EDMF Febuxostat 14...
- CasNo: 144060-53-7
- Molecular Formula: C16H16N2O3S
- Appearance: A WHITE OR WHITE CRYSTALLINE POWDER
- Application: API
- DeliveryTime: 7 days
- PackAge: 15kg/drum
- Port: main ports of China
- ProductionCapacity: 1000 Kilogram/Month
- Purity: 99% up
- Storage: Sealed in store
- Transportation: usual
- LimitNum: 1 Kilogram
- Related Substances: NMT0.1%
- Residue on Ignition: NMT0.5%
- Heavy Metal: NMT0.001%
- Valid Period: 2 years
Superiority
Sinoway's Advantages:
- ISO 9001:2008 certificated company
- SGS Audited Company
- 26-year experienced in pharmaceutical industry
- China office of Fischer Chemicals AG (Switzerland)
Details
|
Product name |
Febuxostat |
|
CAS No. |
144060-53-7 |
|
Molecular Formula |
C16H16N2O3S |
|
Molecular Weight |
316.3748 |
|
Quality Standard |
99% up by HPLC, EDMF |
|
Appearance |
White powder |
|
ITEMS |
SPECIFICATIONS |
RESULTS |
|
CHARACTERISTICS |
A WHITE OR WHITE CRYSTALLINE POWDER |
COMPLIES |
|
IDENTIFICATION |
POSITIVE |
COMPLIES |
|
SOLUBILITY OF SOLUTION AND COLOUR |
COMPLIES |
COMPLIES |
|
ASSAY(BY HPLC) |
98%~102% |
99.7% |
|
RELATED IMPURITIES |
NMT0.1% |
0.1% |
|
LOSS ON DRYING |
NMT0.5% |
0.2% |
|
RESIDUE ON IGNITION |
NMT0.2% |
0.05% |
|
HEAVY METALS |
NMT0.001% |
NMT0.001% |
|
CONCLUSION:THE PRODUCT COMPLIES WITH EDMF STANDARD. |
||
Function of Febuxostat
The main effect of febuxostat is to promote uric acid excretion and inhibit uric acid production.
At present, the drugs for the treatment of elevated uric acid in my country mainly include two categories: 1. Drugs that promote the excretion of uric acid, such as benzbromarone; 2. Drugs that inhibit the production of uric acid, the most representative of which is allopurinol. Febuxostat is a new type of uric acid-lowering drug with a similar mechanism of action to allopurinol, mainly inhibiting xanthinase, thereby inhibiting the production of uric acid. At the same time, febuxostat has less side effects and has less impact on liver and kidney function, especially patients with moderate or lower renal insufficiency can use febuxostat with confidence. At the same time, patients can achieve a good therapeutic effect on gout by cooperating with diet and strict low-purine diet.
