factory supply GMP,DMF Gadobutrol CAS NO.138071-82-6

We are very compeitive on Gadobutrol. Our mfr is DML certified for this item with CEP document.

Product Name:	Gadobutrol
Synonyms:	Gadobutrol;GadoliniuM,[10-[2,3-dihydroxy-1-(hydroxyMethyl)propyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetato(3-)-kN1,kN4,kN7,kN10,kO1,kO4,kO7]-;gallium 10-(1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-tricarboxylate;CL124;gadolinium(III) 2,2',2''-(10-((2R,3S)-1,3,4-trihydroxybutan-2-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate;CS-113;gudobutrol;Ggadobutrol
CAS:	138071-82-6
MF:	C18H31N4O9.Gd
MW:	604.712
EINECS:	1308068-626-2
Product Categories:	API
Mol File:	138071-82-6.mol

Gadobutrol Chemical Properties

Melting point	>264°C (dec.)
density	1.3 g/mL at 37 °C
storage temp.	Refrigerator
solubility	Water (Slightly)
form	Solid
color	White to Off-White
PH	6.6-8
InChIKey	ZPDFIIGFYAHNSK-IWEVFNEWNA-K
SMILES	N1(CCN(CC([O-])=O)CCN(CC([O-])=O)CCN(CC([O-])=O)CC1)[C@H](CO)[C@H](O)CO.[Gd+3] \|&1:24,27,r\|

Gadobutrol Usage And Synthesis

Uses	Gadobutrol is a gadolinium-based MRI contrast agent (GBCA).
Uses	Gadobutrol injection is a magnetic resonance imaging (MRI) contrast agent that is used to help create a clear picture of the body during an MRI scan. MRI scans are a special kind of procedure that lets a doctor look at the inside of the body, such as the brain.
Brand name	Gadobutrol is marketed by Bayer AG as Gadovist, and by Bayer HealthCare Pharmaceuticals as Gadavist. In India, it is also marketed by Vivere Imaging as Viv-butrol.
Mechanism of action	In the central nervous system, Gadobutrol works by highlighting any areas with disrupted blood brain barrier (BBB) and/or abnormal vascularity. In breast tissue, Gadobutrol exposes the presence and extent of malignant breast disease.
Side effects	Side effects of Gadobutrol are uncommon but may include: headache, nausea, vomiting, feeling unwell (malaise), dizziness, abnormal or unpleasant taste in your mouth, feeling hot, numbness or tingly feeling, itching or rash, skin redness, or injection site reactions (cold feeling, warmth, pain, or burning). Its more serious side effects include: urinating less than usual or not at all; drowsiness, confusion, mood changes, increased thirst, loss of appetite; swelling, weight gain, shortness of breath; seizures (convulsions); breathing problems; pounding heartbeats or fluttering in your chest; or severe pain, burning, or irritation around the IV needle.