China (Mainland)
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99% up by HPLC Upadacitinib 1310726-60-3 CAS NO.1310726-60-3
- Min.Order: 25 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,MoneyGram
- Product Details
Keywords
- Upadacitinib 1310726-60-3
- Upadacitinib
- 1310726-60-3
Quick Details
- ProName: 99% up by HPLC Upadacitinib 1310726-60...
- CasNo: 1310726-60-3
- Molecular Formula: C17H19F3N6O
- Appearance: White powder
- DeliveryTime: in 7 days after your payment
- PackAge: 1kg/bag ;25kg/drum
- Port: Shanghai/Beijing/Hangzhou
- ProductionCapacity: 10 Metric Ton/Month
- Purity: 99% up
- Storage: Dry place
- Transportation: cool&dry place
- LimitNum: 25 Kilogram
Superiority
Why is SINOWAY:
1) Specialized in pharmaceutical and healthcare industrial for 34 years.
2) ISO 9001:2015 & SGS audited supplier .
3) Accept various payment terms : T.T 30-60 days.
4) We have warehouse in USA with quickly shipment .
5) We can do different terms of FOB ,CIF/CIP ,DDP ...
Details
|
Product name |
Upadacitinib |
|
CAS No. |
1310726-60-3 |
|
Molecular Formula |
C17H19F3N6O |
|
Molecular Weight |
380.3675696 |
|
Quality Standard |
99% up by HPLC |
|
Appearance |
White to light brown powder |
|
ITEMS |
SPECIFICATION |
RESULT |
|
Appearance |
White to light brown powder |
Off-white powder |
|
Water |
1.8%-2.8% |
0.50% |
|
Residue on ignition |
NMT 0.10% |
0.03% |
|
Heavy metal |
NMT 10 ppm |
Conforms |
|
PSD |
D90 NMT 50μm |
13μm |
|
Residual solvents |
Alcohol: NMT 0.50% |
0.014% |
|
2-Methyltetrahydrofuran: NMT 0.50% |
Not detected |
|
|
Heptane: NMT 0.50% |
0.0087% |
|
|
Ethyl acetate: NMT 0.50% |
0.33% |
|
|
Related substances |
The individual impurity : NMT 0.5% |
0.06% |
|
Total impurity: NMT 1.0% |
0.07% |
|
|
Enantiomer |
NMT 0.15% |
0.05% |
|
Purity |
NLT 99.0% |
99.98% |
|
Conclusion |
The products complies with the enterprise standard |
|
Function of Upadacitinib
Upadatinib is primarily indicated for patients with refractory, moderate-to-severe atopic dermatitis in adults and adolescents 12 years of age and older who have not responded well to or are unsuitable for other systemic therapies (such as hormones or biologics). The launch of upadatinib extended-release tablets provides more options for the treatment of patients with atopic dermatitis. Upatinib works by blocking the activity of Janus kinases in the JAK-STAT signaling pathway. Proinflammatory cytokine stimulation causes inflammation in rheumatoid arthritis, psoriatic arthritis, and atopic dermatitis. The JAK-STAT signaling pathway is an intracellular pathway that plays a major role in the release of pro-inflammatory cytokines.
