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99% up by HPLC PARECOXIB SODIUM 198470-85-8 CAS NO.198470-85-8
- Min.Order: 25 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T
- Product Details
Keywords
- PARECOXIB SODIUM
- PARECOXIB
- 198470-85-8
Quick Details
- ProName: 99% up by HPLC PARECOXIB SODIUM 198470...
- CasNo: 198470-85-8
- Molecular Formula: C19H18N2O4S. Na
- Appearance: White powder
- Application: API
- DeliveryTime: 7 days after payment
- PackAge: 25kg/drum
- Port: shanghai/beijing
- ProductionCapacity: 10 Metric Ton/Month
- Purity: 99% up by HPLC
- Storage: Normal templeture
- Transportation: normal
- LimitNum: 25 Kilogram
Superiority
Why is SINOWAY:
1) Specialized in pharmaceutical and healthcare industrial since 1987
2) ISO 9001:2015 & SGS audited supplier .
3) Accept various payment terms : T.T 30-60 days.
4) We have warehouse in USA with quickly shipment .
5) We can do different terms of FOB ,CIF/CIP ,DDP ...
Details
|
Product name |
Parecoxib Sodium |
|
CAS No. |
198470-85-8 |
|
Molecular Formula |
C19H18N2O4S. Na |
|
Molecular Weight |
392.404 |
|
Molecular Structure |
|
|
Quality Standard |
98.0% up by HPLC |
|
Appearance |
White to almost white crystalline powder |
|
|
|
ANALYSIS |
SPECIFICATION |
RESULTS |
|
Appearance |
White to almost white crystalline powder |
Conform |
|
Identification |
A: The retention time of the main peak of the test solution should be consistent with the retention time of the main peak of the reference solution. |
Conform |
|
B: Comparing with the spectrum obstained with CRS |
Conform |
|
|
C: Reaction of sodium |
Conform |
|
|
Clarity and color solution |
Meets the requirements |
Conform |
|
pH |
7.5-9.0 |
8.3 |
|
Chlorides |
≤ 0.02% |
< 0.02% |
|
Ammonium |
≤ 0.02% |
< 0.02% |
|
Sulfate |
≤ 0.02% |
< 0.02% |
|
Water |
≤ 2.0% |
0.4% |
|
Heavy metals |
≤ 0.002% |
< 0.002% |
|
Propionic acid |
≤ 0.15% |
Not detected |
|
Related substance |
Impurity I ≤ 0.15% |
Not detected |
|
Impurity II ≤ 0.15% |
Not detected |
|
|
Impurity III ≤ 0.15% |
Not detected |
|
|
Impurity IV ≤ 0.15% |
Not detected |
|
|
Impurity V ≤ 0.15% |
Not detected |
|
|
Impurity VI ≤ 0.15% |
Not detected |
|
|
Other single impurity ≤ 0.10% |
Not detected |
|
|
Total impurities ≤ 0.50% |
Not detected |
|
|
Residual solvent |
Ethanol ≤ 5000ppm |
45.3ppm |
|
|
Acetone ≤ 5000ppm |
317.5ppm |
|
|
Dichloromethane ≤ 600ppm |
Not detected |
|
|
Ethyl acetate ≤ 5000ppm |
59.6ppm |
|
|
Triethylamine ≤ 320ppm |
1.0ppm |
|
|
Toluene ≤ 890ppm |
7.7ppm |
|
Endotoxin |
≤ 2.9EU/mg |
< 2.9EU/mg |
|
Microbial limit |
TAMC ≤ 100cfu/g |
< 1cfu/g |
|
TYMC ≤ 10cfu/g |
< 10cfu/g |
|
|
E.Coli: Not detected |
Not detected |
|
|
Assay (anhydrous substance) |
98.0%-102.0% |
100.8% |
|
Conclusion |
The product meets the specification |
|
|
|
What is Parecoxib Sodium
Parecoxib Sodium (SC 69124A) is a highly selective and orally active COX-2 inhibitor, the proagent of Valdecoxib (HY-15762). Parecoxib Sodium is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits prostaglandin (PG) synthesis. Parecoxib Sodium can be used for the relief of acute postoperative pain and symptoms of chronic inflammatory conditions such as osteoarthritis and rheumatoid arthritis in vivo.
