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Home > Products >  factory supply Trilostane

factory supply Trilostane CAS NO.13647-35-3

  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,T/T,Other
  • Product Details

Keywords

  • Trilostane
  • 3β-hydroxysteroid dehydrogenase
  • 13647-35-3

Quick Details

  • ProName: factory supply Trilostane
  • CasNo: 13647-35-3
  • Molecular Formula: C20H27NO3
  • Appearance: White crystallization
  • Application: the treatment of Cushing's syndrome an...
  • DeliveryTime: in two weeks
  • PackAge: 25kg/drum
  • Port: SHANGHAI BEIJING
  • ProductionCapacity: 10 Metric Ton/Day
  • Purity: USP/EP/BP
  • Storage: room temperature
  • Transportation: AIR SEA TRAIN
  • LimitNum: 1 Kilogram

Superiority

We are very compeitive on Trilostane

Product Name: Trilostane
CAS: 13647-35-3
MF: C20H27NO3
MW: 329.43
EINECS: 237-133-0
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;Inhibitor;FULVICIN
Mol File: 13647-35-3.mol
 

Details

Trilostane Chemical Properties
Melting point  264 °C
alpha  D25 +137.4° (c = 1 in pyridine)
Boiling point  467.02°C (rough estimate)
density  1.1213 (rough estimate)
refractive index  1.5614 (estimate)
storage temp.  2-8°C
solubility  DMSO: ≥17mg/mL
pka 8.57±0.70(Predicted)
form  powder
color  white to tan
CAS DataBase Reference 13647-35-3(CAS DataBase Reference)
EPA Substance Registry System Trilostane (13647-35-3)
Trilostane Usage And Synthesis
treatment of Cushing's syndrome Trilostane is an inhibitor of 3β-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome and primary hyperaldosteronism. These are both disorders where excess amounts of corticosteroid hormones are produced in the body. Corticosteroids are essential for the body to make use of carbohydrates, fats and proteins and for a normal response to stress. They are also necessary for the regulation of salt and water balance in the body. Trilostane helps prevent the production of corticosteroids, controlling the symptoms associated with these disorders.
Trilostane can also be useful in the treatment of breast cancer that has relapsed in women who have gone through menopause.
Uses in dogs Trilostane was withdrawn from the United States market in April 1994. However, it was approved in 2008 for the treatment of Cushing's disease (hyperandrenocorticism) in dogs.
It is also the first drug approved to treat both pituitary-and adrenal-dependent Cushing's in dogs.
1. has kidney or liver disease.
2. takes certain medications used to treat heart disease.
3. pregnant.
4. taking other medicines, including those available to buy without a prescription, herbal or complementary medicines.
5. had an allergic reaction to this or any other medicine.
 

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